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\documentclass{presentation}
\title{Development of \\ Frequency Domain Multidimensional Spectroscopy}
\author{Blaise Thompson}
\institute{University of Wisconsin--Madison}
\date{2018-04-23}
%\subject{}
\begin{document}
\maketitle
\section{CMDS} % =================================================================================
\begin{frame}{CMDS}
The Wright Group focuses on the development and usage of \\
Coherent MultiDimensional Spectroscopy (CMDS).
\vspace{\baselineskip} \\
CMDS is a family of related nonlinear spectroscopic experiments.
\end{frame}
\begin{frame}{Why CMDS?}
[A BUNCH OF COOL PUBLICATIONS---FOCUSING ON COHERENCE TRANSFER, MECHANISMS ETC]
[MORE APPLICATIONS]
\end{frame}
\begin{frame}{Coherence transfer}
\fbox{\adjincludegraphics[width=\textwidth]{literature/ChenuAurelia2014a}}
\end{frame}
\begin{frame}{Analytical}
But wait! I'm an \emph{Analytical} Chemist...
\vspace{\baselineskip} \\
What am I doing in a field so rich with fundamental studies?
\vspace{\baselineskip} \\
I hope to convince you that CMDS can be used for analytical work. % TODO: better
\end{frame}
% TODO: in fact, 2DIR is already used regularly...
\begin{frame}{Analytical}
\fbox{\adjincludegraphics[width=\textwidth]{literature/PakoulevAndreiV2009a}}
\end{frame}
% TODO: pakoulev quotes
\begin{frame}{Proteomics}
\fbox{\adjincludegraphics[width=\textwidth]{literature/FournierFrederic2009a}}
\end{frame}
% TODO: fournier quotes
\begin{frame}{Proteomics}
\fbox{\adjincludegraphics[width=\textwidth]{literature/DonaldsonPaulMurray2010a}}
\end{frame}
% TODO: donaldson quotes
\section{Frequency domain} % =====================================================================
\begin{frame}{Domains of CMDS}
CMDS can be collected in two domains:
\begin{itemize}
\item time domain
\item frequency domain
\end{itemize}
\end{frame}
\begin{frame}{Time domain}
Multiple broadband pulses are scanned in \emph{time} to collect a multidimensional interferogram.
\vspace{\baselineskip} \\
A local oscillator must be used to measure the \emph{phase} of the output.
\vspace{\baselineskip} \\
This technique is...
\begin{itemize}
\item fast (even single shot)
\item robust
\end{itemize}
pulse shapers have made time-domain CMDS (2DIR) almost routine.
\end{frame}
\begin{frame}{Frequency domain}
In the Wright Group, we focus on \emph{frequency} domain ``Multi-Resonant'' (MR)-CMDS.
\vspace{\baselineskip} \\
Automated Optical Parametric Amplifiers (OPAs) are used to produce relatively narrow-band pulses.
Multidimensional spectra are collected ``directly'' by scanning OPAs against each-other.
\vspace{\baselineskip} \\
This strategy is...
\begin{itemize}
\item slow (must directly visit each pixel)
\item fragile (many crucial moving pieces)
\end{itemize}
but! It is incredibly flexible.
\end{frame}
\begin{frame}{Bandwidth}
MR-CMDS has no bandwidth limit!
\vspace{\baselineskip} \\
There is just the small matter of making the source continuously tunable...
\adjincludegraphics[width=\textwidth]{opa/OPA_ranges}
\end{frame}
\begin{frame}{Selection rules}
MR-CMDS can easily collect data without an external local oscillator.
\vspace{\baselineskip} \\
This means... [BOYLE]
\end{frame}
\section{The instrument} % =======================================================================
\begin{frame}{The instrument}
[PICTURE OF LASER LAB]
\end{frame}
\begin{frame}{The instrument}
Many kinds of component hardware
\begin{itemize}
\item monochromators
\item delay stages
\item filters
\item OPAs
\end{itemize}
$\sim10$ settable devices, $\sim25$ motors. \\
Multiple detectors.
\end{frame}
\begin{frame}{Pipeline}
\adjincludegraphics[width=0.5\textwidth]{presentation/pipe}
What does the ``pipeline'' of MR-CMDS data acquisition and processing look like in the Wright
Group?
\vspace{\baselineskip} \\
How to increase data throughput and quality, while decreasing frustration of experimentalists? %
\end{frame}
\section{Processing} % ===========================================================================
\begin{frame}{Processing}
WrightTools.
\end{frame}
\begin{frame}{Universal format}
\end{frame}
\begin{frame}{Flexible data model}
\end{frame}
\section{Acquisition} % ==========================================================================
\begin{frame}{Acquisition}
PyCMDS.
\end{frame}
\begin{frame}{Modular hardware model}
\end{frame}
\begin{frame}{Acquisitions}
\end{frame}
\begin{frame}{Queue}
This strategy can be incredibly productive!
\begin{itemize}
\item Soon after the queue was first implemented, we collected more pixels in two weeks than
had been collected over the previous three years.
\end{itemize}
\end{frame}
\section{Tuning} % ===============================================================================
\begin{frame}{Tuning}
\end{frame}
\section{Supplement} % ===========================================================================
\begin{frame}{MR-CMDS theory}
\end{frame}
\begin{frame}{Mixed domain}
[FIGURES FROM DAN'S PAPER]
\end{frame}
\end{document}
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